Ni(II)/Zn Catalyzed Reductive Coupling of Aryl Halides with Diphenylphosphine Oxide in Water
Submitted by Jun Zhu on Fri, 11/01/2013 - 00:49![](http://junzhu.chem8.org/sites/default/files/ol-2011-01141m_0008.gif)
P-Arylation in water has been developed via cross-coupling of aryl halides with diphenylphosphine oxide (Ph2P(O)H) and (RP)-(−)-menthyl benzylphosphinate catalyzed by NiCl2·6H2O/Zn under relatively mild conditions.